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hover_animation=&#8221;none&#8221; alignment=&#8221;center&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][vc_column_text css=&#8221;&#8221; text_direction=&#8221;default&#8221;]\n<p style=\"text-align: left;\">&#8220;\uc81c\uc57d\uc0ac\ub294 \uc2e0\uc57d\uc744 \uc2dc\uc7a5\uc131, \ud5c8\uac00 \uac00\ub2a5\uc131 \ub4f1 \uac70\uc2dc\uc801\uc778 \uad00\uc810\uc5d0\uc11c \ud310\ub2e8\ud569\ub2c8\ub2e4. \ubc18\uba74 \ub9ce\uc740 \ubc14\uc774\uc624\uae30\uc5c5\uc740 \uc57d\ud6a8\uc640 \ud22c\uc790 \uac00\ub2a5\uc131\ubd80\ud130 \ubcf4\uc8e0. \uc2e0\uc57d\uc774 \uc57d\uc774 \ub420 \uc218 \uc788\ub294\uc9c0\ub97c \uae30\uc900\uc73c\ub85c \uc7a1\uc544\uc57c \ub05d\uae4c\uc9c0 \uac08 \uc218 \uc788\ub294\ub370 \uc911\uac04 \ub2e8\uacc4\uae4c\uc9c0\ub9cc \ubcf4\uace0 \uac1c\ubc1c\uc744 \uc9c4\ud589\ud558\uba74 \uacb0\uad6d \uadf8 \uc218\uc900\uc5d0\uc11c \uba48\ucd9c \uc218 \uc788\uc2b5\ub2c8\ub2e4.&#8221;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;\">\uc870\ubbfc\uadfc \ube44\uc5d1\uc2a4\ud50c\ub79c\ud2b8 \ub300\ud45c\ub294 3\uc77c \ub274\ub370\uc77c\ub9ac\uc640\uc758 \uc778\ud130\ubdf0\uc5d0\uc11c \uc774 \uac19\uc774 \ub9d0\ud588\ub2e4. \ubc14\uc774\uc624\uae30\uc5c5\ub4e4\uc758 \uae30\uc220\ub825\uc774 \ub6f0\uc5b4\ub098\uc9c0\ub9cc \uc784\uc0c1 \ub2e8\uacc4\uc5d0\uc11c \uc88c\ucd08\ud558\ub294 \uc0ac\ub840\uac00 \ubc18\ubcf5\ub418\ub294 \ub370\uc5d0\ub294 \uc784\uc0c1\uc744 \ubc14\ub77c\ubcf4\ub294 \uad00\uc810\uc758 \ucc28\uc774\uac00 \uc788\ub2e4\ub294 \uc124\uba85\uc774\ub2e4.<\/p>\n<p style=\"text-align: left;\">\ube44\uc5d1\uc2a4\ud50c\ub79c\ud2b8\ub294 \uac1c\ubc1c\ubd80\ud130 \uc784\uc0c1 \uc804 \uacfc\uc815\uc744 \uc544\uc6b0\ub974\ub294 CDRO \uae30\uc5c5\uc774\ub2e4. \uae30\uc874 \uc784\uc0c1\uc704\ud0c1(CRO) \uc5c5\ubb34\uc5d0 R&amp;D \ube0c\ub9bf\uc9c0\uc5d0 \uae30\ubc18\ud55c \uc804\ub7b5\uc801 \uc784\uc0c1\uac1c\ubc1c\uc744 \uc811\ubaa9\ud588\ub2e4. \ub2e8\uc21c\ud788 \uc815\ud574\uc9c4 \ud504\ub85c\ud1a0\ucf5c\ub300\ub85c \uc784\uc0c1\uc744 \uc218\ud589\ud558\ub294 \uac83\uc774 \uc544\ub2c8\ub77c \uc5f0\uad6c\uac1c\ubc1c, \uc784\uc0c1\uc5d0\uc11c \ud5c8\uac00\uae4c\uc9c0 \uc774\uc5b4\uc9c8 \uc218 \uc788\ub3c4\ub85d \uac1c\ubc1c \uc804\ub7b5\uc744 \ud568\uaed8 \uc124\uacc4\ud558\ub294 \uac83\uc774 \ud575\uc2ec\uc774\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;\">\uad6d\ub0b4 \ubc14\uc774\uc624\ubca4\ucc98\ub4e4\uc740 \uc2e0\uc57d \uac1c\ubc1c \uacfc\uc815\uc5d0\uc11c \uc804\uc784\uc0c1\ubd80\ud130 \uc784\uc0c1\uc744 CRO\uc5d0 \uc704\ud0c1\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\ub2e4. \ubb38\uc81c\ub294 \uc774 \uacfc\uc815\uc5d0\uc11c \uc5f0\uad6c\u2013\ube44\uc784\uc0c1\u2013\uc784\uc0c1 \uac04 \ub2e8\uc808\uc774 \ubc1c\uc0dd\ud55c\ub2e4\ub294 \uc810\uc774\ub2e4. \uc544\ubb34\ub9ac \uc6b0\uc218\ud55c \ud6c4\ubcf4\ubb3c\uc9c8\uc774\ub77c\ub3c4 \uc784\uc0c1 \uc804\ub7b5\uc774 \ucda9\ubd84\ud788 \uc124\uacc4\ub418\uc9c0 \uc54a\uc73c\uba74 \uac1c\ubc1c\uc774 \uc911\ub2e8\ub418\ub294 \uc0ac\ub840\uac00 \uc801\uc9c0 \uc54a\ub2e4.<\/p>\n<p style=\"text-align: left;\">\uc870 \ub300\ud45c\ub294 &#8220;\ubc14\uc774\uc624\ubca4\ucc98\ub294 \uc5f0\uad6c \uc774\ud6c4 \uc784\uc0c1\uc744 CRO\uc5d0 \ub9e1\uae30\ub294 \uad6c\uc870\uc778\ub370 \uc774 \uacfc\uc815\uc5d0\uc11c \uac1c\ubc1c\uc758 \ub9e5\ub77d\uc774 \ub04a\uae34\ub2e4&#8221;\uba70 &#8220;\uc784\uc0c1\uc740 \ub9c8\uc9c0\ub9c9 \uad00\ubb38\uc774 \uc544\ub2c8\ub77c \ucc98\uc74c\ubd80\ud130 \uace0\ub824\ud574\uc57c \ud560 \ucd9c\ubc1c\uc810&#8221;\uc774\ub77c\uace0 \uac15\uc870\ud588\ub2e4. \uc774\uc5b4 &#8220;\uc784\uc0c1 \uc131\uacf5 \uac00\ub2a5\uc131\uc744 \uace0\ub824\ud558\uc9c0 \uc54a\uc740 \ucc44 \uc5f0\uad6c\ub97c \uc9c4\ud589\ud558\uba74 \uacb0\uad6d \uadf8 \ub2e8\uacc4\uae4c\uc9c0\ub9cc \uac00\ub294 \uc2e0\uc57d\uc774 \ub420 \uc218\ubc16\uc5d0 \uc5c6\ub2e4&#8221;\uace0 \uc124\uba85\ud588\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;\">\ube44\uc5d1\uc2a4\ud50c\ub79c\ud2b8\ub294 \uc774 \ub2e8\uc808 \uad6c\uac04\uc744 \uc904\uc774\ub294 \ub370 \ucd08\uc810\uc744 \ub9de\ucd98\ub2e4. \uc5f0\uad6c \ub2e8\uacc4\uc5d0\uc11c \ub3c4\ucd9c\ub41c \ub370\uc774\ud130\uac00 \ube44\uc784\uc0c1\uacfc \uc784\uc0c1\uc73c\ub85c \uc790\uc5f0\uc2a4\ub7fd\uac8c \uc774\uc5b4\uc9c8 \uc218 \uc788\ub3c4\ub85d \uc804\ub7b5\uc744 \uc124\uacc4\ud558\uace0 \uac1c\ubc1c \uc804 \uacfc\uc815\uc744 \uc720\uae30\uc801\uc73c\ub85c \uc5f0\uacb0\ud574 \uc2e0\uc57d \uac1c\ubc1c \uc131\uacf5\ub960\uc744 \ub192\uc774\ub294 \uc5ed\ud560\uc744 \ud55c\ub2e4.<\/p>\n<p style=\"text-align: left;\">\uace0\uac1d\uc0ac\uc778 \ubc14\uc774\uc624 \uae30\uc5c5 3\uacf3\uc774 \uc9c0\ub09c\ud574 \ucf54\uc2a4\ub2e5 \uae30\uc220\ud2b9\ub840\uc0c1\uc7a5\uc744 \uc704\ud55c \uae30\uc220\uc131 \ud3c9\uac00\ub97c \ud1b5\uacfc\ud574 \ubcf8\uaca9\uc801\uc778 \uc0c1\uc7a5 \uc808\ucc28\uc5d0 \ub4e4\uc5b4\uac14\ub2e4.<\/p>\n<p style=\"text-align: left;\">\uae30\uc220\uc131 \ud3c9\uac00\ub294 \ucf54\uc2a4\ub2e5 \uae30\uc220\ud2b9\ub840\uc0c1\uc7a5\uc744 \uc704\ud55c \ud544\uc218 \uc808\ucc28\ub85c \uc0c1\uc7a5\uc744 \uc900\ube44\ud558\ub294 \uae30\uc5c5\uc758 \ud575\uc2ec \uae30\uc220\ub825, \uc131\uc7a5 \uac00\ub2a5\uc131, \uacbd\uc601 \uc804\ub7b5 \ub4f1\uc744 \uba74\ubc00\ud788 \ud3c9\uac00\ud558\uae30 \uc704\ud574 \ub9c8\ub828\ub41c \uc81c\ub3c4\ub2e4. \uc774\ub97c \ud1b5\uacfc\ud558\uae30 \uc704\ud574\uc11c\ub294 \ud55c\uad6d\uac70\ub798\uc18c\uac00 \uc9c0\uc815\ud55c \ub450 \uac1c\uc758 \uc804\ubb38 \ud3c9\uac00\uae30\uad00\uc5d0\uc11c \uac01\uac01 A \ub4f1\uae09\uacfc BBB \ub4f1\uae09 \uc774\uc0c1\uc758 \ud3c9\uac00\ub97c \ubc1b\uc544\uc57c \ud55c\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;\">\ube44\uc5d1\uc2a4\ud50c\ub79c\ud2b8\uc758 \ud575\uc2ec \uacbd\uc7c1\ub825\uc740 \ucef4\ud4e8\ud130 \ubaa8\ub378\ub9c1\uc744 \uc774\uc6a9\ud55c \ube44\uc784\uc0c1-\uc784\uc0c1 \uc5f0\uacc4 \uc804\ub7b5\uc778 &#8216;MIDD(Model-Informed Drug Development)&#8217;\ub2e4. \ube44\uc784\uc0c1 \ubc0f \uc784\uc0c1 \ub370\uc774\ud130\ub97c \uae30\ubc18\uc73c\ub85c \uc0dd\ubb3c\ud559\uc801\u00b7\ud1b5\uacc4\ud559\uc801 \ubaa8\ub378\uc744 \uad6c\ucd95\ud574 \uc784\uc0c1 \uacb0\uacfc\ub97c \uc0ac\uc804\uc5d0 \uc608\uce21\ud558\uace0, \ud544\uc694\ud558\uba74 \ube44\uc784\uc0c1 \ub2e8\uacc4\uc5d0\uc11c \uc124\uacc4\ub97c \ubcf4\uc644\ud55c\ub2e4.<\/p>\n<p style=\"text-align: left;\">\uc870 \ub300\ud45c\ub294 &#8220;\ubaa8\ub378\ub9c1\uacfc \uc2dc\ubbac\ub808\uc774\uc158\uc744 \ud1b5\ud574 \uc784\uc0c1 \uacb0\uacfc\ub97c \uc608\uce21\ud588\ub294\ub370 \uacb0\uacfc\uac00 \uc81c\ub300\ub85c \ub098\uc624\uc9c0 \uc54a\uc73c\uba74 \ube44\uc784\uc0c1\uc73c\ub85c \ub3cc\uc544\uac00 \ucd08\uae30\uc6a9\ub7c9 \ub4f1 \uc5ec\ub7ec \uc694\uc18c\ub97c \uc870\uc808\ud55c \ub2e4\uc74c \uc784\uc0c1\uc5d0 \ub4e4\uc5b4\uac04\ub2e4&#8221;\uba74\uc11c &#8220;\ube44\uc6a9 \ubd80\ub2f4 \ub54c\ubb38\uc5d0 \uc774 \uacfc\uc815\uc744 \uac74\ub108\ub6f0\uace0 \uc784\uc0c1\uc5d0 \ub4e4\uc5b4\uac00\uba74 \uc2e4\ud328\ud558\ub294 \uc0ac\ub840\uac00 \ub9ce\ub2e4&#8221;\uace0 \uc124\uba85\ud588\ub2e4.<\/p>\n<p style=\"text-align: left;\">\uae40\ud76c\uc120 \ube44\uc5d1\uc2a4\ud50c\ub79c\ud2b8 \ub300\ud45c\ub294 &#8220;\uc784\uc0c1\uc740 \uacc4\ud68d\ub41c \ud504\ub85c\ud1a0\ucf5c\uc744 \uadf8\ub300\ub85c \uc218\ud589\ud558\ub294 \uacfc\uc815\ub9cc\uc774 \uc544\ub2c8\ub77c \uc9c4\ud589 \uc911\uc5d0\ub3c4 \uc774 \uc784\uc0c1\uc774 \uc131\uacf5\ud560 \uc218 \uc788\ub294\uc9c0 \uacc4\uc18d \uc810\uac80\ud558\uace0 \uc870\uc815\ud558\ub294 \uc77c&#8221;\uc774\ub77c\uba70 &#8220;\ud658\uc790\uac00 \ubaa8\uc9d1\ub410\ub2e4\uace0, \uacb0\uacfc\uac00 \ub098\uc654\ub2e4\uace0 \ub05d\uc774 \uc544\ub2c8\ub77c \uadf8 \uacb0\uacfc\uac00 \ud5c8\uac00\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\ub294\uc9c0\ub97c \ub04a\uc784\uc5c6\uc774 \ud655\uc778\ud574\uc57c \ud55c\ub2e4&#8221;\uace0 \ub9d0\ud588\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\" style=\"text-align: left;\"><strong>\uc758\ub8cc\uae30\uae30, \ucc28\uc138\ub300 \ubaa8\ub2ec\ub9ac\ud2f0\ub85c \uc784\uc0c1 \ud655\uc7a5 \u2026 &#8220;\ub9de\ucda4\ud615 \uc804\ub7b5\uc774 \uc911\uc694&#8221;<\/strong><\/p>\n<p style=\"text-align: left;\">\ube44\uc5d1\uc2a4\ud50c\ub79c\ud2b8\ub294 \uc758\uc57d\ud488\ubfd0 \uc544\ub2c8\ub77c \uc758\ub8cc\uae30\uae30 \ubd84\uc57c\uc5d0\uc11c\ub3c4 \uc784\uc0c1 \uc5ed\ub7c9\uc744 \ud655\uc7a5\ud558\uace0 \uc788\ub2e4. \uae40 \ub300\ud45c\ub294 &#8220;\uc758\ub8cc\uae30\uae30\ub294 \uc758\uc57d\ud488\uacfc \ub2ec\ub9ac \uc784\uc0c1 \uc124\uacc4\uc640 \ud5c8\uac00 \uc804\ub7b5\uc774 \ud6e8\uc52c \ub2e4\uc591\ud558\ub2e4&#8221;\uba70 &#8220;\uc784\uc0c1 \ub2e8\uacc4\uc5d0\uc11c\ubd80\ud130 \uaddc\uc81c \ud658\uacbd\uacfc \uc0ac\uc5c5\ud654\ub97c \ud568\uaed8 \uace0\ub824\ud574\uc57c\ud55c\ub2e4&#8221;\uace0 \ub9d0\ud588\ub2e4.<\/p>\n<p style=\"text-align: left;\">\ub610\ud55c \ud68c\uc0ac\ub294 siRNA \ub4f1 \uc0c8\ub85c\uc6b4 \ubaa8\ub2ec\ub9ac\ud2f0(\uce58\ub8cc\uc811\uadfc\ubc95) \uc784\uc0c1\uc5d0\ub3c4 \uc801\uadf9\uc801\uc73c\ub85c \ucc38\uc5ec\ud558\uace0 \uc788\ub2e4. \ube44\uc5d1\uc2a4\ud50c\ub79c\ud2b8\ub294 \uad6d\ub0b4 \ucd5c\ucd08\ub85c siRNA \uae30\ubc18 \uce58\ub8cc\uc81c\uc758 IND(\uc784\uc0c1\uc2dc\ud5d8\uacc4\ud68d) \uc2b9\uc778\uc744 \uc131\uc0ac\uc2dc\ucf30\ub2e4. \uae40 \ub300\ud45c\ub294 &#8220;\uac01 \uae30\uc220\uc5d0 \ub9de\ub294 \ub9de\ucda4\ud615 \uc784\uc0c1 \uc804\ub7b5\uc774 \ud544\uc694\ud558\ub2e4&#8221;\uba74\uc11c &#8220;\uc81c\uc57d\uc0ac \uacbd\ud5d8\ub4e4\uc744 \ub9ce\uc774 \ubcf4\uc720\ud558\uace0 \uc788\uc5b4 \uc784\uc0c1\uc5d0 \ud544\uc694\ud55c \ucd5c\uc801\uc758 \uc870\ud569\uc744 \uc870\uc9c1\ud560 \uc218 \uc788\ub2e4&#8221;\uace0 \uac15\uc870\ud588\ub2e4.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left;\">\ube44\uc5d1\uc2a4\ud50c\ub79c\ud2b8\uc758 \ucc28\ubcc4\ud654 \uc9c0\uc810\uc740 \uc2a4\uc2a4\ub85c\ub97c CRO(\uc784\uc0c1\uc218\ud0c1\uae30\uc5c5)\uac00 \uc544\ub2cc CDRO(\uc784\uc0c1\uac1c\ubc1c\u00b7\uc218\ud0c1\uae30\uc5c5)\ub85c \uaddc\uc815\ud558\ub294 \ub370 \uc788\ub2e4. \ub2e8\uc21c\ud788 \uc815\ud574\uc9c4 \ud504\ub85c\ud1a0\ucf5c\uc744 \uc218\ud589\ud558\ub294 \uc6a9\uc5ed \uc870\uc9c1\uc774 \uc544\ub2c8\ub77c \uac1c\ubc1c \uc804\ub7b5 \uc218\ub9bd\ubd80\ud130 \uc784\uc0c1 \uc6b4\uc601, \uae00\ub85c\ubc8c \ud655\uc7a5\uae4c\uc9c0 \uc804 \uacfc\uc815\uc744 \uc124\uacc4\ud558\ub294 \uac1c\ubc1c \ud30c\ud2b8\ub108\ub77c\ub294 \uc124\uba85\uc774\ub2e4.<\/p>\n<p style=\"text-align: left;\">\uc870 \ub300\ud45c\ub294 &#8220;CRO\ub294 \uacb0\uad6d CDRO\ub85c \uac00\uc57c \ud55c\ub2e4&#8221;\uba70 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